An article in Science (Volume 391, Issue 6787, Pages 777-779, February 2026) describes how bacteria deliver a microtubule-binding protein to mammalian cells to promote colonization. Authors are Michael S. Costello, Bryan Neumann and others. The study focuses on the mechanism that allows bacteria to enter host cells through this protein. The protein binds to microtubules in mammalian cells, facilitating bacterial colonization. Research identifies this process as key to bacterial pathogenicity. A major finding is that protein delivery promotes successful tissue colonization.[8]