Precision-oriented medicine brings a transformational approach to the rehabilitation of patients with non-infectious diseases, which, instead of traditional symptom relief and functional capacity improvement, emphasizes individualized strategies that take into account the patient's genetics, environment and lifestyle[1]. Modern technologies such as digital health tools, artificial intelligence, and telemedicine enable remote patient monitoring, customized exercise programs, and immediate feedback to increase adherence to treatment plans and optimize outcomes[1]. New therapeutic techniques including motor imagery, virtual reality and neurostimulation show significant potential in addressing the physical and cognitive challenges associated with non-infectious diseases[1]. Accuracy-oriented rehabilitation is a dynamic process as patients with non-communicable diseases go through different phases of stability and deterioration[6]. This integrated approach combines physical health, psychological well-being and social factors into a unified system of care[1]. The PREPARE research project is developing an artificial intelligence platform to stratify patients and predict rehabilitation outcomes for the nine most common diagnoses, including Parkinson's disease, back disorders and hypertension[5].