Pancreatic cancer evades the immune system by using a sugar-coated protective signal on the surface of tumor cells. Scientists at Northwestern Medicine discovered this mechanism and developed a new antibody that removes this protective signal. In tests on animals, after the application of the antibody, the immune cells were reactivated and began to fight against the tumor. The result was a significant slowing of tumor growth compared to untreated animals. This antibody represents a new approach to the treatment of pancreatic cancer, which is known for its aggressiveness and difficult treatment. The research team is currently refining the therapy in order to prepare it for clinical trials in human patients.