Scientists have achieved a new breakthrough in CRISPR technology, which allows genes to be turned on without physically interrupting the DNA molecule. Instead of cutting DNA, they use a method of removing chemical tags that act as molecular anchors and actively silence genes. The discovery confirms a long-standing scientific hypothesis that these chemical markers play a key role in gene regulation. This more subtle form of gene editing represents a safer approach to treating genetic diseases, such as sickle cell disease, which could be treated by reactivating the gene in fetal blood. The main advantage of this method is to reduce the risk of unintended side effects compared to traditional DNA cutting methods. Scientists say the discovery opens up new possibilities for effective and safer genetic therapies.