In 2024, 105,922 new HIV diagnoses were reported in the European region in 49 out of 53 countries, corresponding to a crude rate of 11.8 cases per 100,000 population. In the EU/EEA countries, both new diagnoses and AIDS-related deaths have decreased. More than half of HIV diagnoses in Europe in 2024 were detected at a late stage of the disease. The majority of new cases in Europe were transmitted through heterosexual contact (62%), followed by sex between men (13%) and injecting drug use (12%). 7 161 AIDS cases were reported in 2024, the actual number may be higher. There is still a significant number of people living with HIV without a diagnosis. ECDC calls for a holistic approach: removing stigma, increasing testing and ensuring quality care for all.