The study analysed data from 12,807,473 bloodstream infection (BSI) susceptibility tests from 29 European countries in 2015-2019 for 8 bacteria according to EARS-Net and produced projections of the burden of antimicrobial resistance (AMR) by 2050, taking into account demographic changes, age and gender.[2][4] Rates of BSI are projected to increase more in males than females for 6 of the 8 bacteria and significantly in the 74+ age group, while stabilizing or declining in younger groups.[1][3] Failure to account for age and sex leads to different projections, e.g. fewer cases in males in 76% (29/38) of bacteria and antibiotic combinations[2] By 2050, large differences between countries are expected, e.g. for aminoglycoside-resistant Acinetobacter spp. a relative difference from 0.34 to 15.38 by 2030. Achieving a 10% reduction in resistant BSI by 2030 was only possible for 68.4% (26/38) of combinations, even with a reduction in incidence of 20 per 100,000 persons per year, followed by a resurgence in some cases.[2][6] The inclusion of country-, age-, and sex-specific levels of resistance strongly influences projections of the burden of AMR in Europe[3].